Publications

FGFR2 fusion-driven cholangiocarcinoma is characterized by a distinct neutrophil-enriched tumor microenvironment in a syngeneic murine model
Nugzar Lekiashvili, Trinh Kieu Dinh, Alexander Olkus, Yu-Le Wu 6 Chun-Shan Liu, Daria Komkova, Albrecht Stenzinger, Felix J. Hartmann, Thomas Longerich, Michael T. Dill
JHEP Reports (2026); https://doi.org/10.1016/j.jhepr.2026.101964

Peptide Thioester and Triazole Derivatives Through On-Resin Dual-Modification of Peptide Thiosulfonates
Marius Werner, Agnes Bergmann, Chenxi Liu, Mira Behnam, Christian Klein, Franziska Thomas
Angewandte Chemie International Edition (2026): e8315692, https://doi.org/10.1002/anie.8315692

Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors
Zhaoqing Hu, Hitoshi Matsuo, Shangce Du, Cecilia Berzain Battioni, Lena Jassowicz, Rafael Carretero, Melanie Sator-Schmitt, Xiyue Zhao, Beiping Miao, Cansu Eris, Helena Engel, Mohamed A.A. Mahmoud, Elke Laport, Yanling Xiao, Ilse Hofmann, Christel Herold-Mende, Chong Sun
Immunity (2026); 0. https://doi.org/10.1016/j.immuni.2026.06.006

IDH1-mutant vaccine in newly diagnosed astrocytoma: final analysis of the multicenter, single-arm, open-label, first-in-human phase 1 NOA16 trial
Lukas Bunse, Katharina Lindner, Antje Wick, Angelika Freitag, Lisa-Marie Lanz, Dominic Edelmann, Abigail Suwala, Michael O. Breckwoldt, Inga Harting, Felix Sahm, Richard F. Schlenk, Anita Schmitt, Oliver Schnell, Jörg Hense, Martin Misch, Dietmar Krex, Monika Denk, Juliane Walz, Joachim P. Steinbach, Andreas von Deimling, Michael Schmitt, Theresa Bunse, Ghazaleh Tabatabai, Martin Bendszus, Isabel Poschke, Wolfgang Wick & Michael Platten
Nat Cancer (2026). https://doi.org/10.1038/s43018-026-01199-y

Stress granule phase separation in stress-responsive cytosolic extract-in-oil droplets
Aline Lieber, Oskar Staufer, Zhaozhi Sun, Ulrike Engel, Charlotte Flory, Nathan Mikhaylenko, Kevin Jahnke, Katja Kopp, Philipp Klein, Sarah Hofmann, Oliver T. Fackler, Pavel Ivanov, Ilia Platzman, Pietro Scaturro, Joachim P. Spatz & Alessia Ruggieri
Nat Commun 17, 5011 (2026). https://doi.org/10.1038/s41467-026-73936-x

Late-Stage Functionalization of Peptides on the Solid Phase
Marius Werner, Truc Lam Pham, Franziska Thomas
Angewandte Chemie International Edition (2026): e4556652, https://doi.org/10.1002/anie.4556652

DNA origami-based virus-like particles: a new class of HIV vaccine candidates with superior immunogenic properties
Frauke Muecksch, Juan Hamdan & Oliver T. Fackler
Sig Transduct Target Ther 11, 193 (2026). https://doi.org/10.1038/s41392-026-02735-z

Regulation of immune checkpoint molecules in cancer immune evasion and therapy.
Cansu Eris, Cheng Zu, Yanling Xiao, Michael Platten & Chong Sun
Nat Rev Cancer (2026). https://doi.org/10.1038/s41568-026-00934-y

A tissue-intrinsic mechanism sensitizes HIV-1 particles for TLR-triggered innate immune responses
Samy Sid Ahmed, Liv Zimmermann, Andrea Imle, Katrin Wuebben, Nadine Tibroni, Lena Rauch-Wirth, Jan Münch, Petr Chlanda, Frederik Graw & Oliver T. Fackler
Nat Commun 17, 4209 (2026). https://doi.org/10.1038/s41467-026-72586-3

Phage-assisted evolution of allosteric protein switches.
Nicholas T. Southern, Anna von Bachmann, Alisa Hovsepyan, Marielouise Griebl, Benedict Wolf, Nina Lemmen, Ann-Sophie Kroell, Simon Westermann, Jan Mathony & Dominik Niopek
Nat Commun 17, 3498 (2026). https://doi.org/10.1038/s41467-026-71717-0

Programmable Edge-to-Edge Assembly of RNA Nanostructures
Cody Geary, Mai P. Tran, Erik Poppleton, Alena Taskina, Kerstin Göpfrich
bioRxiv 2026.03.29.714238; doi: https://doi.org/10.64898/2026.03.29.714238

Volume and surface methods for microparticle traction force microscopy: a computational and experimental comparison
Simon Brauburger, Bastian K. Kraus, Tobias Walther, Cornelis Mense, Tobias Abele, Kerstin Göpfrich, Ulrich S. Schwarz
Soft Matter 2026; https://doi.org/10.1039/d6sm00242k

Buoyancy-driven sorting of synthetic cells for nanopore activity
Maja Lehr, Mattea Unger, Tobias Abele, Stefan J. Maurer, Dirk Flemming, Kerstin Göpfrich
bioRxiv 2026.02.03.702772. doi: https://doi.org/10.64898/2026.02.03.702772

Bioswitches: Towards programmable, on-demand control of therapeutic proteins.
Benedict Wolf, Jan Mathony, Dominik Niopek
Clin Transl Med. 2026;16(2):e70612. doi:10.1002/ctm2.70612